The use of a formula-based ketogenic diet in children with refractory epilepsy.
نویسندگان
چکیده
The ketogenic diet (KD) is a nonpharmacologic treatment that has been used for refractory epilepsy since 1921. The KD is a high-fat, low-carbohydrate, and restricted protein diet, which is calculated and weighed for each individual patient. Introducing and maintaining the diet for a long time remains a challenge. In this study, we evaluated the acceptability, tolerance, and efficacy of a formula-based KD in 10 children with refractory epilepsy. The ketogenic formula tested herein caused only mild KD-related adverse events and adequate adherence. Moreover, 60% of patients had more than 50% seizure frequency reduction and 10% were seizure-free.
منابع مشابه
Assessment and follow up of the children with refractory epilepsy on ketogenic diet
Introduction: The ketogenic diet is a method of treatment that is recommended for patients with epilepsy who have not responded to medications. The present study was designed to evaluate the efficacy of the ketogenic diet along with follow-up on drug resistant epilepsy in children referred to medical centers affiliated to Shiraz University of Medical Sciences. Methods: This study was a multicen...
متن کاملEfficiency of the ketogenic diet: treatment of refractory childhood epilepsy
This review reports on the past, current and potential future developments in aspects of the ketogenic diet in epilepsy treatment for children who have refractory epilepsy (uncontrolled seizures after having tried at least two anti-epileptic drugs). The ketogenic diet is based on putting the body into ketosis, so that is uses ketones rather than glucose for the energy in the brain. The diet com...
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BackgroundAbout 15 to 40% of children with seizures are refractory to standard anti-epileptic drugs and for such patients, other treatments such as surgery and the ketogenic diet can reduce seizure frequency. Melatonin is a natural pineal gland hormone. The use of melatonin for controlling pediatric seizures is still controversial. This study aimed to evaluate the effect of melatonin on seizure...
متن کامل[Ketogenic diet for the treatment of refractory epilepsy].
OBJECTIVES To systematically review and synthesize the available evidence on the efficacy of the ketogenic diet in reducing seizure frequency for children with refractory epilepsy. DATA SOURCES Medline searches were performed using the keywords epilepsy/therapy, dietary therapy, and epilepsy, and the text word ketogenic diet. The Cochrane Library of clinical trials was searched using the term...
متن کاملمقایسه اثر گاماگلوبولین وریدی با رژیم کتوژنیک در کودکان مبتلا به صرع مقاوم
Since of seizures in epileptic is in childhood in 80% of cases and 10 to 20% of these seizures are refractory to treatment , this study was performed ...
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ورودعنوان ژورنال:
- Arquivos de neuro-psiquiatria
دوره 75 4 شماره
صفحات -
تاریخ انتشار 2017